Prof. Wiesław Nowiński

Brain Atlases With Fast Warping For Neurosurgery and Stroke

While brain atlas-to-neuroimage registration is commonly recognized for its role in segmenting and annotating neuroimages, its clinical applications extend far beyond these basic tasks. In stereotactic and functional neurosurgery, individualized brain atlases facilitate surgical planning by delineating target structures in multiple planes, identifying structures along the planned trajectory, reducing the number of microelectrode insertions, and guiding the placement of therapeutic lesions. In stroke, brain atlases localize ischemic lesions, enable quantification of infarct and penumbra volumes, differentiate ischemic from hemorrhagic stroke, and facilitate outcome prediction.

This talk presents the construction of brain atlases for clinical applications, fast registration methods, and atlas-enabled applications, spanning both research and commercial domains. The brain atlas-to-image registration methods include the fast Talairach transformation with an automatic calculation of the modified Talairach landmarks and ellipse fitting-based registration.